Semaglutide TFA is a long-acting, selective GLP-1R agonist that penetrates the blood-brain barrier. It promotes insulin secretion, inhibits gastric emptying and appetite, and enhances autophagy. It is used in research for conditions like type 2 diabetes, obesity, Parkinson's disease, and fatty liver disease.
- GLP-1R agonist.
- Blood-brain barrier penetration.
- Promotes insulin, inhibits gastric emptying/appetite.
- Enhances autophagy.
- Inhibits oxidative stress and apoptosis.
- Regulates mitochondrial and lipid metabolism.
- Lowers blood sugar; reduces weight.
- Neuroprotective effects.
- Improves hepatic steatosis.
- Research on neurodegenerative/liver diseases.